US EPA

4848521 

Journal Article 

Benchmark experiment for the cross section of the Mo-100(p,2n)Tc-99m and Mo-100(p,pn)Mo-99 reactions 

Takacs, S; Ditroi, F; Aikawa, M; Haba, H; Otuka, N 

2016 

1 

Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
ISSN: 0168-583X 

375 

60-66 

10.1016/j.nimb.2016.03.040 

WOS:000375808400011 

As nuclear medicine community has shown an increasing interest in accelerator produced Tc-99m radionuclide, the possible alternative direct production routes for producing Tc-99m were investigated intensively. One of these accelerator production routes is based on the Mo-100(p,2n)Tc-99m reaction. The cross section of this nuclear reaction was studied by several laboratories earlier but the available data-sets are not in good agreement. For large scale accelerator production of Tc-99m based on the (100)mMo(p,2n)Tc-99m reaction, a well-defined excitation function is required to optimise the production process effectively. One of our recent publications pointed out that most of the available experimental excitation functions for the Mo-100 (p,2n)(99)mTc reaction have the same general shape while their amplitudes are different. To confirm the proper amplitude of the excitation function, results of three independent experiments were presented (Takacs et al., 2015). In this work we present results of a thick target count rate measurement of the E-gamma = 140.5 keV gamma-line from molybdenum irradiated by E-p = 17.9 MeV proton beam, as an integral benchmark experiment, to prove the cross section data reported for the Mo-100(p,2n)Tc-99m and Mo-100(p,pn)Mo-99 reactions in Takacs et al. (2015). (C) 2016 Elsevier B.V. All rights reserved. 

Tc-99m; Mo-99; Thick target count rate; Cross section; Cyclotron