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HERO ID
4902955
Reference Type
Journal Article
Title
Solubility of Losartan potassium in different binary solvents from (293.15 to 343.15) K
Author(s)
Guo, Kun; Yin, Q; Zhang, M; Wang, J
Year
2008
Is Peer Reviewed?
Yes
Journal
Journal of Chemical and Engineering Data
ISSN:
0021-9568
EISSN:
1520-5134
Volume
53
Issue
5
Page Numbers
1138-1140
DOI
10.1021/je700724r
Web of Science Id
WOS:000255655900015
Abstract
The solubility of losartan potassium in mixed 2-propanol + water and 2-propanol + cyclohexane solvents was measured at the temperature ranging from (293.15 to 343.15) K under atmospheric pressure. The experimental data were correlated by the CNIBS/Redlich-Kister model. The results show that the solubility of losartan potassium increases with increasing temperature in these two binary mixed solvents and increases with the increasing mole fraction of water while decreasing mole fraction of cyclohexane, respectively.
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