US EPA

505913 

Journal Article 

An Update on Osteoporosis 

Nochowitz, B; Siegert, S; Wasik, M 

2009 

Yes 

American Journal of Therapeutics
ISSN: 1075-2765
EISSN: 1536-3686 

16 

5 

437-445 

English 

Osteoporosis is a skeletal disease that currently affects more than 25 million men and women in the United States. This silent affliction presents asymptomatically as the compromised bone composition in the body goes unrealized and may ultimately lead to fractures. Without treatment or preventative measures, the risks of morbidity and mortality are increased. Complications arising from osteoporosis are often a result of disease-related fractures, which can lead to decreased efficiency of activities of daily life, disabling pain, loss of independent living, and, in some instances, death. Early diagnosis is crucial, and treatment or prevention is highly recommended for the most optimal outcome. Individualized therapy is necessary due to the multitude of therapeutic options. As the population of Americans older than 65 years is expected to double by the year 2050, osteoporosis prevention and treatment will be vital to effective patient care. 

bisphosphonates; calcium; calcitonin; estrogen replacement therapy; hormone replacement therapy; osteoporosis; osteopenia; selective; estrogen receptor modulators; teriparatide; randomized controlled-trial; postmenopausal osteoporosis; atrial-fibrillation; vertebral fractures; zoledronic acid; hip; fracture; risk-factors; women; alendronate; bisphosphonates