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5082313 
Journal Article 
Analysis of trifluoroacetic acid and other short-chain perfluorinated acids (C2-C4) in precipitation by liquid chromatography-tandem mass spectrometry: comparison to patterns of long-chain perfluorinated acids (C5-C18) 
Taniyasu, S; Kannan, K; Yeung, LW; Kwok, KY; Lam, PK; Yamashita, N 
2008 
Yes 
Analytica Chimica Acta
ISSN: 0003-2670
EISSN: 1873-4324 
619 
2 
221-230 
English 
18558116 
WOS:000257644100010 
A method has been developed to measure 29 perfluorinated acids (PFAs) including short-chain perfluorocarboxylates (PFCAs) such as trifluoroacetic acid (TFA; C2) and long-chain PFCAs, perfluoroalkylsulfonates, fluorotelomer acids, and two perfluorooctylsulfonamides in water matrices. The method involves solid phase extraction (SPE) using a weak anion-exchange (WAX) cartridge, an ion-exchange high-performance liquid chromatography (HPLC) column separation, and tandem mass spectrometry (MS/MS) detection. To our knowledge, this is the first HPLC-MS/MS method to determine TFA in water at sub-ng L(-1) concentrations. The method is selective, simple, and robust, capable of measuring 29 PFAs in a single analysis, with overall recoveries of the target analytes ranging from 75% to 132%. The method was applied to the analysis of rainwater samples collected from two cities in Japan. TFA and several short-chain PFAs were the major compounds found in rainwater. 
Trifluoroacetic acid; Perfluorochemicals; Perfluorooctanoic acid; Perfluorooctanesulfonate; Ion exchange