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5098639 
Journal Article 
Influence of storage conditions on the characteristics of digoxin-Emcompress tablets 
Vila Jato, JL; Concheiro, A; Torres, D 
1985 
1 
S
ISSN: 1874-9062 
1 
Mar 1985 
IPA COPYRIGHT: ASHP A factorial design was used to study the influence of storage time, temperature and humidity on a number of technological parameters of 0.25 mg digoxin tablets containing 10% wheat starch and Emcompress (calcium phosphate dibasic dihydrate). The response surfaces obtained show that, after 9 months storage under certain conditions, the percentage of digoxin dissolved after one h by tablets formed under a compressional force of 4100 N fails to reach the minimum required by USP XXI.