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5127088 
Journal Article 
Hydroxylation of 3,4-benzpyrene in human fetal tissue homogenates 
Juchau, MR; Pedersen, MG; Symms, KG 
1972 
Yes 
Biochemical Pharmacology
ISSN: 0006-2952
EISSN: 1873-2968 
PERGAMON-ELSEVIER SCIENCE LTD 
OXFORD 
21 
16 
2269-2272 
English 
4630402 
WOS:A1972M915400014 
IPA COPYRIGHT: ASHP The detection of 3,4-benzypyrene hydroxylation catalyzed by an enzyme system referred to as aryl hydrocarbon hydroxylase or benzpyrene hydroxylase, in several organisms of the human feto-placenta unit at 13-20 weeks of gestation is reported. The activity of this enzyme system in fetal tissues may be a highly important determinant of human fetal pharmacology and toxicology.