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HERO ID
5124197
Reference Type
Journal Article
Title
Carcinogenic property of JBO(P) variety of jute batching oil
Author(s)
Mehrotra, NK; Kumar, S; Antony, M
Year
1988
Is Peer Reviewed?
Yes
Journal
Drug and Chemical Toxicology
ISSN:
0148-0545
EISSN:
1525-6014
Publisher
Informa Healthcare
Volume
11
Issue
2
Page Numbers
181-193
Language
English
PMID
3402349
DOI
10.3109/01480548808998221
Abstract
The topical application of neat JBO-P variety of jute batching oil (JBO) three times a week has been found to produce skin tumours locally with 13 weeks of treatment on Swiss albino mice. In another set of experiments, 3 times/week topical application of JBO on Swiss albino mouse skin previously initiated (s.c., 1 mg/g body wt.) with urethane resulted in induction of tumours (squamous cell papillomas and keratoacanthomas) in 8 weeks. These results suggest that the JBO-P variety of jute batching oil could be a complete carcinogen or a tumour promoting substance on mouse skin.
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