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HERO ID
5198985
Reference Type
Journal Article
Title
Characterization of collagen from normal human sclera
Author(s)
Keeley, FW; Morin, JD; Vesely, S
Year
1984
Is Peer Reviewed?
Yes
Journal
Experimental Eye Research
ISSN:
0014-4835
EISSN:
1096-0007
Volume
39
Issue
5
Page Numbers
533-542
Language
English
PMID
6519194
Abstract
Human scleral tissue contains approximately 50% collagen by weight, consisting predominantly of type I collagen. There is little or no evidence for the presence of substantial quantities of type II, type III or other collagen types. There appears to be no difference in either collagen content or genetic type in sclera between adult and juvenile tissues or between anterior and posterior segments of the sclera, although, with increased age there is a marked increase both in the extent of glycosylation of the collagen and its resistance to solubilization by treatment with pepsin.
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