TISSUE DISTRIBUTION AND TEMPERATURE-DEPENDENCE OF XENOBIOTIC HYDROLYSIS IN THE DUNGENESS CRAB (CANCER-MAGISTER) | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

5220440

Reference Type

Journal Article

Title

TISSUE DISTRIBUTION AND TEMPERATURE-DEPENDENCE OF XENOBIOTIC HYDROLYSIS IN THE DUNGENESS CRAB (CANCER-MAGISTER)

Author(s)

Swall, LM; Tjeerdema, RS

Year

1991

Is Peer Reviewed?

Yes

Journal

Aquatic Toxicology
ISSN: 0166-445X
EISSN: 1879-1514

Publisher

Elsevier Science, P.O. Box 211 Amsterdam 1000 AE

Volume

Issue

1-2

Page Numbers

1-11

Language

English

DOI

10.1016/0166-445X(91)90037-A

Web of Science Id

WOS:A1991GC65500001

URL

https://search.proquest.com/docview/14272165?accountid=171501
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Abstract

Tissue samples from the dungeness crab were exposed to radiolabeled methyl palmitate to investigate the distribution of xenobiotic hydrolytic activity and its dependence on water temperature. Exposed tissue samples from the hepatopancreas, gill, muscle, and cardiac stomach were monitored at 8, 13, and 18 degree C. The hepatopancreas rapidly hydrolyzed methyl palmitate, and the reaction was strongly temperature-dependent. Hydrolysis in the other tissues was limited, with only cardiac stomach exhibiting both consistent activity at low levels and strong temperature-dependence. Hydrolysis of methyl palmitate indicated an ability to detoxify the sorbitan polyoxyethylene esters in chemical oil spill dispersants, organophosphorus and carbamate pesticides, and phthalic acid esters. In all tissues, the hydrolysis of methyl palmitate yielded palmitic acid as the only metabolite.

Keywords

METHYL PALMITATE; CANCER-MAGISTER; HYDROLYSIS; XENOBIOTIC BIOTRANSFORMATION