US EPA

5322656 

Journal Article 

EFFECTS OF FATTY ACIDS AT DIFFERENT POSITIONS IN THE TRIGLYCERIDES ON CHOLESTEROL LEVELS 

Teh, SSin; Voon, PTee; Ng, YenT; Ong, SH; Ong, ASH; Choo, YMay 

2016 

28 

2 

211-221 

WOS:000379214500009 

Previous studies established a series of regression equations for predicting the risk factor effects from serum cholesterol concentrations. However, the degree of saturation was solely based on total fatty acid composition in triglycerides. Our article is focused on the relationships between the published human nutrition studies and predicted values of serum cholesterol levels based on total fatty acid compositions and at sn-2 position in triglycerides. Twenty-two published human nutrition studies were chosen to assess the effects of palm olein, olive oil, cocoa butter, sunflower seed oil, corn oil, soyabean oil, grapeseed oil, groundnut oil and rice bran oil diets on serum cholesterol levels. There were no statistically significant differences between the predicted values of serum cholesterol levels based on fatty acids at sn-2 position and the published human nutrition studies as proven by the statistical analyses with p values more than 0.05. In contrast, there were statistically significant differences between the predicted values of serum cholesterol levels based on total fatty acids and the published human nutritional studies with p values less than 0.05. Fatty acids at sn-2 position appear to influence the cholesterol levels rather than total fatty acids of the triglyceride. 

fatty acid compositions; sn-2 position; serum cholesterol concentrations; experimental value; predicted value