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5370161 
Journal Article 
Correlation of delayed hypersensitivity and leukocyte migration inhibition factor in the serum of cancer patients 
Botto, HG; Gauthier, H; Pouillart, P; Bruley-Rosset, M; Huguenin, P 
1977 
Yes 
European Journal of Cancer
ISSN: 0959-8049
EISSN: 1879-0852 
13 
4-5 
329-332 
English 
194777 
Cellular immunity was evaluated in patients with three types of cancers: squamous cell bronchial carcinoma, breast carcinoma and glioblastoma multiformis. Delayed hypersensitivity skin responses to DNCB as primary antigen and to PPD, candidin and mumps as recall antigens were measured in these patients. At the same time, the presence of leucocyte inhibition factor (LIF) in the serum was assayed. A good correlation between the degree of inhibition of migration and the size of the skin reaction was found in patients with bronchus and breast carcinoma but not glioblastoma. Following these patients up during the course of their disease, by the in vivo and in vitro tests, a good evaluation of the immunological reactivity of the patients could be obtained. © 1977. 
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