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537997 
Journal Article 
The synthesis and testing of arenearylpyrimidylmethanes as antimalarial agents 
Yepuri, NR; Haritakul, R; Griffith, R; Leach, SP; Keller, PA 
2006 
0 
ChemMedChem
ISSN: 1860-7179
EISSN: 1860-7187 
1 
7 
715-+ 
English 
16902924 
WOS:000202946000009 
Do the two-step: A new convergent synthesis of the arenearylpyrimidylmethane (AAPM) scaffold requires only two steps, and subsequent derivatisation yielded the potent lead 1 against a multidrug-resistant malarial strain. The presence of atropisomerism with this class of compounds is also reported.