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5415335 
Book/Book Chapter 
Anesthetic Gases 
Clar, DT; Richards, JR 
2019 
StatPearls Publishing 
Treasure Island (FL) 
StatPearls 
English 
Anesthetic gases (nitrous oxide, halothane, isoflurane, desflurane, sevoflurane), also known as inhaled anesthetics, are administered as primary therapy for preoperative sedation and adjunctive anesthesia maintenance to intravenous (IV) anesthetic agents (i.e., midazolam, propofol) in the perioperative setting.[1] Inhaled anesthetics enjoy regular use in the clinical setting due to chemical properties that allow rapid introduction of an agent into arterial blood via the pulmonary circulation as compared to the more circuitous route of venous circulation.[2] The significance of rapid therapeutic effects allows for efficient induction and discontinuation of sedation induced by these agents; providing proper amnesia, anesthesia, and a faster recovery period in postoperative care as compared to IV agents.[3] 
PFAS
• PFAS 150
     Literature Search Update December 2020
          PubMed
     Literature Search August 2019
          PubMed
     Not prioritized for screening
     Sevoflurane
     1,1,1,3,3,3-Hexafluoro-2- (fluoromethoxy)propane
• PFAS Universe
     Data Source
          Pubmed
     Isoflurane