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5441830 
Journal Article 
Haloalkane dehalogenase caught in the act 
Prince, RC 
1994 
Trends in Biochemical Sciences
ISSN: 0968-0004 
19 
3-4 
English 
Understanding the biodegradation of halogenated compounds is a timely goal. Several bacteria are able to use 1,2-dichloroethane as the sole source of carbon and reductant, including Xanthobacter autotrophicus GJ10. Two dehalogenases have been identified in the organism, one capable of dehalogenating alkanes, the other of dehalogenating carboxylic acids. Crystallography characterizes the haloalkane dehalogenase in essentially all three phases of the catalytic cycle. 
haloalkane dehydrogenase; X-ray crystallography; 1,2-dichloroethane; carbon sources; Pollution Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Xanthobacter autotrophicus; biodegradation; A 01006:Enzymes & cofactors; P 2000:FRESHWATER POLLUTION