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Citation
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HERO ID
5441830
Reference Type
Journal Article
Title
Haloalkane dehalogenase caught in the act
Author(s)
Prince, RC
Year
1994
Is Peer Reviewed?
1
Journal
Trends in Biochemical Sciences
ISSN:
0968-0004
Volume
19
Issue
1
Page Numbers
3-4
Language
English
URL
https://search.proquest.com/docview/16991927?accountid=171501
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Abstract
Understanding the biodegradation of halogenated compounds is a timely goal. Several bacteria are able to use 1,2-dichloroethane as the sole source of carbon and reductant, including Xanthobacter autotrophicus GJ10. Two dehalogenases have been identified in the organism, one capable of dehalogenating alkanes, the other of dehalogenating carboxylic acids. Crystallography characterizes the haloalkane dehalogenase in essentially all three phases of the catalytic cycle.
Keywords
haloalkane dehydrogenase; X-ray crystallography; 1,2-dichloroethane; carbon sources; Pollution Abstracts; Microbiology Abstracts A: Industrial & Applied Microbiology; Xanthobacter autotrophicus; biodegradation; A 01006:Enzymes & cofactors; P 2000:FRESHWATER POLLUTION
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