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HERO ID
5453336
Reference Type
Journal Article
Title
Synthesis, spectral and antimicrobial evaluation of some new 8-membered phosphorus heterocyclic compounds
Author(s)
Kumar, KA; Reddy, CS; Reddy, CD
Year
2003
Is Peer Reviewed?
1
Journal
Indian Journal of Chemistry. Section B
ISSN:
0376-4699
EISSN:
0975-0983
Publisher
NATL INST SCIENCE COMMUNICATION & INFORMATION RESOURCES-NISCAIR
Location
NEW DELHI
Volume
42
Issue
10
Page Numbers
2589-2594
Language
English
Web of Science Id
WOS:000186135500008
Abstract
Several new 8-membered phosphours heterocyclic compounds such as 2,10-dichloro-6-aryloxy/arylthio-12-trichloromethyl-12H-dibenzo[d,g][1,3,2] dioxaphosphocin-6-sulfides 4a-i have been synthesized by the cyclocondensation of 2,2-bis(2-hydroxy-5-chlorophenyl) 1,1,1-trichloroethane 1 with thiophosphorylchloride 2 in the presence of base in dry toluene followed by addition of different phenols/thiophenols. The chemical structures of all the products are confirmed by analytical, IR, NMR (1H, 13C & 31P) and mass spectral studies. Their bio-assay showed them to possess significant antibacterial and antifungal activity.
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