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5453336 
Journal Article 
Synthesis, spectral and antimicrobial evaluation of some new 8-membered phosphorus heterocyclic compounds 
Kumar, KA; Reddy, CS; Reddy, CD 
2003 
Indian Journal of Chemistry. Section B
ISSN: 0376-4699
EISSN: 0975-0983 
NATL INST SCIENCE COMMUNICATION & INFORMATION RESOURCES-NISCAIR 
NEW DELHI 
42 
10 
2589-2594 
English 
Several new 8-membered phosphours heterocyclic compounds such as 2,10-dichloro-6-aryloxy/arylthio-12-trichloromethyl-12H-dibenzo[d,g][1,3,2] dioxaphosphocin-6-sulfides 4a-i have been synthesized by the cyclocondensation of 2,2-bis(2-hydroxy-5-chlorophenyl) 1,1,1-trichloroethane 1 with thiophosphorylchloride 2 in the presence of base in dry toluene followed by addition of different phenols/thiophenols. The chemical structures of all the products are confirmed by analytical, IR, NMR (1H, 13C & 31P) and mass spectral studies. Their bio-assay showed them to possess significant antibacterial and antifungal activity.