Health & Environmental Research Online (HERO)


Print Feedback Export to File
551361 
Journal Article 
Group 6 Fischer carbene complexes: "Chemical multitalents" for multi-component reactions 
Barluenga, J; Fernández-RodrIguez, MA; Aguilar, E 
2005 
Yes 
Journal of Organometallic Chemistry
ISSN: 0022-328X
EISSN: 1872-8561 
690 
3 
539-587 
English 
WOS:000226883700001 
The ability of heteroatom stabilized Fischer carbene complexes (FCCs) to participate in multicomponent reactions, which has allowed the construction of a large variety of highly functionalized structures through several patterns of reactivity, will be disclosed along the following lines. One of the main reasons for the high versatility and often unexpected behavior of FCCs relies on the possibility of incorporation of carbonyl ligands along the reaction pathway, depending on the reaction conditions. Thus, in this review there will be presented examples where up to five components react in a multicomponent sequence to create up to nine carbon-carbon bonds or to lead to the formation of up to seven stereogenic centers what points out the undisputable synthetic potential of FCCs.