Preparative-scale one-pot syntheses of hexafluoro-1,3-butadiene | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

5692065

Reference Type

Journal Article

Title

Preparative-scale one-pot syntheses of hexafluoro-1,3-butadiene

Author(s)

Ramachandran, PV; Reddy, GV

Year

2008

Is Peer Reviewed?

Yes

Journal

Journal of Fluorine Chemistry
ISSN: 0022-1139
EISSN: 1873-3328

Volume

129

Issue

Page Numbers

443-446

DOI

10.1016/j.jfluchem.2008.01.015

Web of Science Id

WOS:000255990600019

URL

http://www.sciencedirect.com/science/article/pii/S0022113908000419
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Abstract

Hexafluoro-1,3-butadiene, with its negligible global warming potential, is required in quantities for application in plasma dielectric etching in semiconductor industry and as gaseous microbubble suspension contrast agents in diagnostic ultrasound imaging. Three efficient protocols for the preparation of perfluoro-1,3-butadiene in 62–70% overall yields have been described. They involve the coupling of (1) iodotrifluoroethylene (ITFE) with activated copper, (2) trifluorovinylzinc bromide in the presence of copper (II) or iron (III) salts and (3) trifluorovinylzinc chloride, prepared from 1,1,1,2-tetrafluorethane (HFC 134a) in the presence of copper (II) or iron (III) salts.

Keywords

Etching-gases; Ultrasound contrast agents; Gaseous microbubbles; Hexafluoro-1,3-butadiene; Coupling reaction; Bromortrifluoroethylene