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580009 
Journal Article 
Bacterial Adhesion and Entry into Host Cells 
Pizarro-Cerdá, J; Cossart, P 
2006 
Yes 
Cell
ISSN: 0092-8674
EISSN: 1097-4172 
124 
4 
715-727 
Successful establishment of infection by bacterial pathogens requires adhesion to host cells, colonization of tissues, and in certain cases, cellular invasion--followed by intracellular multiplication, dissemination to other tissues, or persistence. Bacteria use monomeric adhesins/invasins or highly sophisticated macromolecular machines such as type III secretion systems and retractile type IV pili to establish a complex host/pathogen molecular crosstalk that leads to subversion of cellular functions and establishment of disease.