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5925671 
Journal Article 
Heated Tobacco Products: Volatile Emissions and Their Predicted Impact on Indoor Air Quality 
Cancelada, L; Sleiman, M; Tang, X; Russell, ML; Montesinos, VN; Litter, MI; Gundel, LA; Destaillats, H 
2019 
1 
Environmental Science & Technology
ISSN: 0013-936X
EISSN: 1520-5851 
53 
13 
7866-7876 
English 
31150216 
WOS:000474478300069 
This study characterized emissions from IQOS, a heated tobacco product promoted as a less harmful alternative to cigarettes. Consumable tobacco plugs were analyzed by headspace GC/MS to assess the influence of heating temperature on the emission profile. Yields of major chemical constituents increased from 4.1 mg per unit at 180 °C to 6.2 mg at 200 °C, and 10.5 mg at 220 °C. The Health Canada Intense smoking regime was used to operate IQOS in an environmental chamber, quantifying 33 volatile organic compounds in mainstream and sidestream emissions. Aldehydes, nitrogenated species, and aromatic species were found, along with other harmful and potentially harmful compounds. Compared with combustion cigarettes, IQOS yields were in most cases 1-2 orders of magnitude lower. However, yields were closer to, and sometimes higher than electronic cigarettes. Predicted users' daily average intake of benzene, formaldehyde, acetaldehyde and acrolein were 39 μg, 32 μg, 2.2 mg and 71 μg, respectively. Indoor air concentrations were estimated for commonly encountered scenarios, with acrolein levels of concern (over 0.35 μg m-3) derived from IQOS used in homes and public spaces. Heated tobacco products are a weaker indoor pollution source than conventional cigarettes, but their impacts are neither negligible nor yet fully understood. 
Environmental Studies; Indoor air quality; Volatile organic compounds--VOCs; Cigarettes; Tobacco; Benzene; Organic compounds; Emissions; Aromatic compounds; Environmental chambers; Test chambers; Air quality; Acrolein; Headspace; Emission analysis; Indoor air pollution; Cigarette smoking; Acetaldehyde; Indoor environments; Organic chemistry; Smoking; Aldehydes; Environmental impact; Public spaces; Impact prediction; 31223:Tobacco Manufacturing