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5939069 
Journal Article 
Effect of electrostatic potential of transition state on the stereo selectivity in ene cyclisation: A theoretical study 
Roy, S; Chakrabarty, K; Mondal, N; Das, GK 
2006 
1 
Indian Journal of Chemistry. Section A
ISSN: 0376-4710
EISSN: 0975-0975 
45 
1 
45-50 
English 
WOS:000234851300005 
Investigation on the transition structure of the ene reaction between propyne and formaldehyde reveals that negative electrostatic potential is generated around the carbonyl oxygen and acetylenic group. The generated electrostatic potential ; controls the orientation of the oxygenated substituent present on the forming cyclohexane ring in ene cyclisation, Data from the study of mono substituted transition structures have been used to rationalize the stereoselectivity of an ene cyclisation with poly oxygenated substituents.