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HERO ID
5970019
Reference Type
Journal Article
Subtype
Review
Title
Analgesic-like activity of essential oils constituents
Author(s)
de Sousa, DP
Year
2011
Is Peer Reviewed?
1
Journal
Molecules
ISSN:
1420-3049
Volume
16
Issue
3
Page Numbers
2233-2252
Language
English
PMID
21383660
DOI
10.3390/molecules16032233
Web of Science Id
WOS:000288853400020
Abstract
Research on neuroactive drugs is a pharmaceutical sector of high interest and growth. The discovery of efficient drugs that can relieve pain is a subject of research in the pharmaceutical industry and academic field because pain is a symptom of many diseases. This review will summarize results on the discovery of essential oil constituents with analgesic-like activity from the chemical and pharmacological perspectives. Overall, 43 bioactive compounds were selected in nociception models. Among them, 62.8% were monoterpenes, 18.6% sesquiterpenes and other constituents represented 18.6%. The data show the potential of this group of natural product chemicals as analgesic drugs that may be useful for therapeutic purposes.
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