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6026013 
Journal Article 
Studies on Acute In Vivo Exposure of Rats to 2450-MHz Microwave Radiation. 1. Mast Cells and Basophils 
Galvin, MJ; Mcree, DI; Ortner, MJ 
1981 
1 
Radiation Research
ISSN: 0033-7587
EISSN: 1954-2002 
86 
3 
580-588 
Eight-hour continuous exposure to 2450-MHz microwave radiation in rats was carried out at incident power densities that cause no apparent temperature increase (2 and 10 mW/cm super(2)). The peritoneal mast cells were unchanged in their viability, percentage, toluidine blue metachromasia, histamine content, or size. Isolated mast cells from control and irradiated rats responded in a similar manner to drugs that stimulate histamine secretion via both the chemical (compound 48/80, a condensation product of p)-methoxy-N)-methyl phenethylamine and formaldehyde) and imunological (concanvalin A) pathways. The release of histamine in vivo) from basophils and mast cells was determined by intravenous injection of 48/80 into anesthetized rate. Rats subjected to both levels of irradiation were similar to the controls in their initial blood pressures and their hyposensitive response to 48/80. We have thus shown that the microwave frequency and power densities used in these experiments do not impair normal function in the histamine-secreting cells of the rat. 
exposure; microwaves; density; cellular biology; basophils; biology; Health & Safety Science Abstracts; microwave radiation; irradiation; H SM7.1:BASIC APPROACHES, CONCEPTS, AND THEORY