US EPA

602793 

Journal Article 

Preparation of poly(vinylidene fluoride) microfiltration membrane with uniform surface-copolymerized poly(ethylene glycol) methacrylate and improvement of blood compatibility 

Chang, Y; Shih, YJ; Ruaan, RC; Higuchi, A; Chen, WY; Lai, JY 

2008 

Yes 

Journal of Membrane Science
ISSN: 0376-7388 

309 

1/2 

165-174 

10.1016/j.memsci.2007.10.024 

WOS:000252813000019 

Abstract: This work describes the surface modification and characterization of poly(vinylidene fluoride) (PVDF) microfiltration (MF) membranes grafted with poly(ethylene glycol) methacrylate (PEGMA) via surface-activated ozone treatment and thermally induced graft copolymerization. The chemical composition and microstructure of the surface-modified PVDF membranes were characterized by Fourier transform infrared spectroscopy (FT-IR), contact angle, and atomic force microscopy (AFM) measurements. Blood compatibility of the modified membranes was evaluated by the biofouling property of the platelet adhesion observed by scanning electron microscopy (SEM) and the plasma protein adsorption determined by an enzyme-linked immunosorbent assay (ELISA). In general, the grafting density of the copolymerized PEGMA and the hydrophilicity on the surface of PVDF MF membranes increase with increasing macromonomer concentration of PEGMA in the reaction solution. The grafting distribution of PEGMA on the resulting membranes was found to form a uniform polymer hydrogel-like layer controlled by sufficient high content of PEGMA in the reaction solution, while their surface roughness was kept lower than that of the virgin membrane. For the platelet adhesion test, a remarkable suppression of the platelets adhered to the PVDF MF membranes grafted with PEGMA polymer was observed. In the water flux experiments, the PEGMA-grafted hydrophilic PVDF MF membranes exhibited good anti-fouling properties to substantially reduce the irreversible membrane fouling caused by platelet adhering and plasma protein adsorption as compared with the virgin hydrophobic PVDF MF membranes. [Copyright 2008 Elsevier] Copyright of Journal of Membrane Science is the property of Elsevier Science Publishers B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts) 

ETHYLENE glycol; METHYL methacrylate; SEPARATION (Technology); PLANT propagation