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6034452 
Journal Article 
Influence of seven immunostimulants on the immune response of coho salmon to Aeromonas salmonicida 
Albright, LJ; Evelyn, TPT; Nikl, L 
1991 
Yes 
Diseases of Aquatic Organisms
ISSN: 0177-5103
EISSN: 1616-1580 
12 
1 
7-12 
A study was conducted to evaluate the efficacy of 7 substances at potentiating a formalin-killed Aeromonas salmonicida bacterin in juvenile coho salmon Oncorhynchus kisutch . The substances were injected into the fish along with the bacterin. The fish were challenged 27 d later with viable A. salmonicida cells by 2 methods (cohabitation and immersion). The cumulative mortalities in each of the experimental groups was then determined. A significant and consistent increase in protection over the groups receiving only the A. salmonicida bacterin was observed with 3 of the substances tested. These were VitaStim-Taito, lentinan and formalin-killed Renibacterium salmoninarum cells. One of these materials, VitaStim-Taito (a beta -1,3 glucan), showed particular promise for further studies. 
bacterial diseases; fish culture; fish diseases; immune response; immunostimulants; ASFA 1: Biological Sciences & Living Resources; ASFA 3: Aquatic Pollution & Environmental Quality; Microbiology Abstracts A: Industrial & Applied Microbiology; Immunology Abstracts; Microbiology Abstracts B: Bacteriology; Oceanic Abstracts; ASFA Aquaculture Abstracts; biotechnology; vaccines; therapy; Oncorhynchus kisutch; Aeromonas salmonicida; bacterins; immunization; A 01102:Bacteria and fungi; Q1 08582:Fish culture; O 5060:Aquaculture; J 02834:Vaccination and immunization; Q1 08484:Species interactions: parasites and diseases; Q3 08582:Fish culture; F 06807:Active immunization