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HERO ID
6060711
Reference Type
Journal Article
Title
Cytomorphologic features of sebaceous carcinoma on fine needle aspiration
Author(s)
Stern, RC; Liu, K; Dodd, LG
Year
2000
Is Peer Reviewed?
Yes
Journal
Acta Cytologica
ISSN:
0001-5547
Volume
44
Issue
5
Page Numbers
760-764
Language
English
PMID
11015976
DOI
10.1159/000328558
Abstract
OBJECTIVE:
To describe three cases of sebaceous carcinoma metastatic to regional lymph nodes diagnosed by fine needle aspiration (FNA).
STUDY DESIGN:
FNA was performed using standard techniques. A portion of each specimen was stained with Diff-Quick (Dade, Miami, Florida, U.S.A.); another portion was fixed in 95% ethanol and stained with a modified Papanicolaou stain or fixed in formalin and stained with hematoxylin and eosin.
RESULTS:
All carcinomas were moderately cellular, with primarily irregular cell clusters. The cytoplasm was finely reticular and contained variable numbers of small vaculoes. Nuclei were centrally located and pleomorphic and contained coarse chromatin. Variably sized but often large nucleoli were seen. Mitotic figures were easily identified.
CONCLUSION:
Sebaceous carcinoma is a rare but cytologically distinct neoplasm. It frequently metastasizes to regional lymph nodes and may then appear as a mass amenable to FNA. Aspiration cytologists, particularly those who aspirate head and neck lesions, should be familiar with the distinct features of this neoplasm.
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