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606296 
Journal Article 
Toad skin-secretions: Potent source of pharmacologically and therapeutically significant compounds 
Garg, AD; Hippargi, RV; Gandhare, AN 
2008 
5 
2 
17-17 
Amphibians have been occupying a wide range of habitats since they evolved around 363 million-years-ago. Along with legs and lungs, skin played an important role in survival of amphibians and made it possible for them to exploit diverse ecological conditions. Amphibian skin not only helps in avoiding desiccation but also helps in imposing defense against predators as well as pathogens. Amphibian skin possesses wide variety of chemical compounds, which have potential significance in pharmacology and therapeutics. Toads especially those belonging to genus Bufo, are outstanding source of useful granular-gland secretions. Compounds derived from toad skin-secretions can be used as analgesics, painkillers and as medicine against cardiac-problems, multi-drug resistant bacteria, HIV and Cancer. [ABSTRACT FROM AUTHOR] Copyright of Internet Journal of Pharmacology is the property of Internet Scientific Publications LLC and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts) 
MEDICINE -- Research; CLINICAL medicine; DRUG development; PHARMACOLOGY; AMPHIBIANS; PATHOGENIC microorganisms; Bufadienolides; Bufo; Toad Skin-Secretions; Toxins