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6067437 
Journal Article 
BIOERODIBLE POLYANHYDRIDES FOR CONTROLLED DRUG DELIVERY 
Rosen, HB; Chang, J; Wnek, GE; Linhardt, RJ; Langer, R 
1983 
Yes 
Biomaterials
ISSN: 0142-9612
EISSN: 1878-5905 
Elsevier 
4 
2 
131-133 
English 
6860755 
WOS:A1983QQ00800013 
Initial in vitro and in vivo (rat) studies using a poly(anhydride), poly[bis(p-carboxyphenoxy)methane], as a bioerodible matrix for controlled drug delivery are described. Drug delivery matrices fabricated from this material and containing cholic acid showed a period of nearly zero-order erosion kinetics during which this steroid was released at nearly the same constant rate. 
Drugs; drug delivery system; polymer; polyanhydride; bioerosion