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6134121 
Journal Article 
Heterocyclische Spirocyclohexadienone aus substituierten Phenolen / Heterocyclic Spirocyclohexadienones from Substituted Phenols 
Möhrle, H; Schake, D 
2014 
Verlag der Zeitschrift für Naturforschung 
Zeitschrift für Naturforschung B 
50, no. 12 
1859-1868 
Mannich bases were prepared from substituted phenols with aliphatic amines and formaldehyde. Amine exchange with N-methyl-2-naphthylamine followed by a Hofmann Martius rearrangement gave rise to o,o′-amino-hydroxy-diphenylmethane derivatives. Under cyclization conditions some of these compounds produced spirocyclohexadienones, which are the ipso analogs to the hypothetic intermediates postulated in the aminomethylation mechanism of phenols. 
amines; aminomethylation; formaldehyde; phenols; Internet resource