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620522 
Journal Article 
Synthesis and Structure of Mycolactone E Isolated from Frog Mycobacterium 
Sylvain, A; Richard, EL; Engy, AM; Pam, LCS; Dia, B; Yoshito, K 
2008 
1 
Organic Letters
ISSN: 1523-7060
EISSN: 1523-7052 
10 
23 
5385-5388 
The structure of mycolactone E, isolated from the frog pathogen Mycobacterium liflandii, was established via organic synthesis. Within the mycolactone family of metabolites, a structural variation has been seen only at the unsaturated fatty acid moiety thus far, and mycolactone E follows this observation. Interestingly, the absolute configuration of its unsaturated fatty acid matches that of the mycolactones from human mycobacteria, rather than the structurally more closely related mycolactone F from fish mycobacteria. [ABSTRACT FROM AUTHOR] Copyright of Organic Letters is the property of American Chemical Society and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts) 
LACTONES; MYCOBACTERIUM; PATHOGENIC bacteria; ORGANIC compounds -- Synthesis; METABOLITES; UNSATURATED fatty acids