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625515 
Journal Article 
Letter 
Toxicity of butylated hydroxytoluene 
Shlian, DM; Goldstone, J 
1986 
New England Journal of Medicine
ISSN: 0028-4793
EISSN: 1533-4406 
314 
10 
648-649 
English 
To the Editor: Recently, we have observed that a number of our university students are taking large doses of butylated hydroxytoluene (BHT), a phenolic antioxidant food preservative, as treatment for genital herpes simplex virus (HSV) infections. Relying on statements made in Pearson and Shaw's best-selling book, The Life Extension Companion,1 these students take 2 to 6 g of BHT per day. The book recommends maintenance doses of at least 2 g per day, taken at bedtime on an empty stomach. The 250-mg capsules are available in most health food stores. Although no well-controlled clinical trials have been reported, there. © 1986, Massachusetts Medical Society. All rights reserved.