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625652 
Technical Report 
NTP 
Eleventh report on carcinogens: Nitrofen (2,4-dichlorophenyl-p-nitrophenyl ether) CAS No. 1836-75-5 
National Toxicology Program :: NTP 
2005 
National Toxicology Program, Department of Health and Human Services 
Research Triangle Park, NC 
Report on Carcinogens, Eleventh Edition 
1 
is a chapter of 093207 11th Report on carcinogens
Nitrofen is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals (NCI 1978, 1979, IARC 1983). When administered in the diet, technical grade nitrofen increased the incidences of hepatocellular carcinomas and adenomas in mice of both sexes, hemangiosarcomas of the liver or spleen in male mice, and anaplastic adenocarcinomas of the pancreas in female rats.