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6305497 
Journal Article 
Cimetidine—A Non-Thiourea H2-Receptor Antagonist 
Brimblecombe, RW; Duncan, WAM; Durant, GJ; Emmett, JC; Ganellin, CR; Parsons, ME 
1975 
Yes 
Journal of International Medical Research
ISSN: 0300-0605
EISSN: 1473-2300 
3 
2 
86-92 
Cimetidine is a non-thiourea analogue of metiamide. It is a specific competitive histamine H2-receptor antagonist and is an effective inhibitor of gastric secretion in animals and man with similar pharmacological properties to metiamide. No renal damage or haematological changes were observed in 90-day studies in rats or dogs.