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6327626 
Journal Article 
Relationship of Caffeine with Adiponectin and Blood Sugar Levels in Subjects with and without Diabetes 
Bhaktha, G; Nayak, BS; Mayya, S; Shantaram, M 
2015 
Journal of Clinical and Diagnostic Research
ISSN: 2249-782X
EISSN: 0973-709X 
9 
1 
BC01-BC03 
English 
25737971 
INTRODUCTION: Coffee though not usually thought of as healthy food but can be treated as one of the beneficial drink. Many researchers have found strong evidence that coffee reduces the risk of several serious ailments, including diabetes, heart disease, cirrhosis of the liver, etc. The long term beneficial effect of coffee on diabetes is now understood to be more influential and obliging.

MATERIALS AND METHODS: This study comprised 220 healthy subjects of which 143 consumed coffee and 77 did not. These were matched with 90 diabetic subjects. Among the 90 diabetics, 48 consumed coffee and 42 did not consume coffee.

RESULTS: The mean adiponectin value was significantly higher in coffee consumed normal and diabetic subjects than the subjects who did not consume coffee. The decrease in fasting blood sugar and HbA1c values were also observed in normal and diabetic subjects who consumed coffee than the other groups who did not consume coffee. Significant difference (p<0.05) in mean FBG, PPBS, HbA1c and adiponectin were observed between coffee consumed and no coffee consumed groups.

CONCLUSION: The long term use of caffeine is more efficient on blood sugar and adiponectin levels, which needed in the prevention of complications in diabetic subjects.