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6400435 
Journal Article 
The danger of "yellow dyes" (tartrazine) to allergic subjects 
Neuman, I; Elian, R; Nahum, H; Shaked, P; Creter, D 
1978 
Yes 
Clinical Allergy
ISSN: 0009-9090 
8 
1 
65-68 
English 
627044 
WOS:A1978EM57400009 
Oral administration of 50 mg tartrazine to 122 patients with a variety of allergic disorders caused the following reactions: general weakness, heatwaves, palpitations, blurred vision, rhinorrhoea, feeling of suffocation, pruritus and urticaria. There was activation of the fibrinolytic pathway as shown by reduction of plasminogen with high pre-kallikrein and low kallikrein values. Reduction in complement activity (CH50) was seen in three out of sixteen reactions.