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6429028 
Journal Article 
Review 
[Leptin] 
Sabath Silva, EF 
2002 
1 
Revista de Investigacion Clinica
ISSN: 0034-8376
EISSN: 2385-3956 
54 
2 
161-165 
Spanish 
12053815 
Leptin is a hormone secreted by adipocytes, stomach and placenta. Age, sex, puberty onset and food intake are the most important physiological factors that determines leptin concentration. It has been shown that leptin secretion is regulated by other hormones such as insulin, glucocorticoids and sex steroids. Leptin has an important role in hungry and satiety regulation as well as in normal sexual maturation. There have been some studies in obese subjects showing promising results with leptin administration.