Jump to main content
US EPA
United States Environmental Protection Agency
Search
Search
Main menu
Environmental Topics
Laws & Regulations
About EPA
Health & Environmental Research Online (HERO)
Contact Us
Print
Feedback
Export to File
Search:
This record has one attached file:
Add More Files
Attach File(s):
Display Name for File*:
Save
Citation
Tags
HERO ID
6430232
Reference Type
Journal Article
Title
Determinants of bone mass and size in 7-year-old former term, late-preterm, and preterm boys
Author(s)
Abou Samra, H; Stevens, D; Binkley, T; Specker, B
Year
2009
Is Peer Reviewed?
1
Journal
Osteoporosis International
ISSN:
0937-941X
EISSN:
1433-2965
Volume
20
Issue
11
Page Numbers
1903-1910
Language
English
PMID
19308302
DOI
10.1007/s00198-009-0896-z
Abstract
UNLABELLED:
When compared, full-term prepubertal boys had greater regional bone size, higher total body (TB) bone mineral content (BMC), and regional bone density than preterm boys but higher TB bone content area and regional BMC than late-preterm boys. Implications include follow-up bone assessment and preterm formula feeding in late-preterm boys.
INTRODUCTION:
This study was conducted to determine whether there are differences in bone mass and size among prepubertal boys born preterm (PT; < or =34 weeks gestation), late-preterm (LP; >34 and < or =37 weeks gestation), and at term (>37 weeks gestation) and to identify factors that are associated with bone mass and size in these children.
METHODS:
Total body (TB), spine and hip dual energy X-ray absorptiometry and tibia peripheral quantitative computed tomography measures were obtained on 24 boys aged 5.7 to 8.3 years.
RESULTS:
In multiple regression analysis adjusting for current weight, height, age, and jump power, term boys had greater cortical thickness (p = 0.03) and area (p = 0.01), higher trabecular volumetric bone mineral density (p = 0.05), TB bone mineral content (BMC; p = 0.007), and hip areal bone mineral density (aBMD; p = 0.01) than PT boys, and higher TB BMC (p = 0.01), TB bone area (p = 0.03), hip BMC (p = 0.02) and aBMD (p = 0.01), and femoral neck BMC (p = 0.05) and aBMD (p = 0.02) than LP boys. There were no differences in activity measures among gestation groups and no group-by-activity interactions.
CONCLUSION:
Term boys have greater bone size and mass than PT boys and higher bone mass than LP boys at several bone sites. Activity measures did not differ among gestation groups and did not explain bone differences.
Home
Learn about HERO
Using HERO
Search HERO
Projects in HERO
Risk Assessment
Transparency & Integrity