Health & Environmental Research Online (HERO)


Print Feedback Export to File
6574565 
Journal Article 
Amino acids excess increase SCEs in human lymphocytes 
Clevidence, BA; He, G; Xing, BW; Na, R; , 
1996 
1 
Mutation Research
ISSN: 0027-5107
EISSN: 1873-135X 
English 
9003533 
The effects of 21 amino acids on sister-chromatid exchanges (SCEs) in human lymphocytes were investigated. Addition of each of the 21 amino acids, originally in a composition of the culture medium RPMI 1640, at three different concentrations (10 micrograms/ml, 50 micrograms/ml and 100 micrograms/ml) caused a dose-independent increase in SCE frequency. The results indicated that amino acids, although indispensable for cells in vivo and in vitro, may be SCE-inducing agents.