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6597417 
Journal Article 
Catalytic asymmetric cyclopropanation of heteroaryldiazoacetates 
Davies, HM; Townsend, RJ; , 
2001 
Yes 
Journal of Organic Chemistry
ISSN: 0022-3263
EISSN: 1520-6904 
AMER CHEMICAL SOC 
WASHINGTON 
6595-6603 
English 
11578209 
WOS:000171407700012 
Rh(2)(S-DOSP)(4)-catalyzed decomposition of heteroaryldiazoacetates in the presence of styrene results in highly diastereoselective and enantioselective cyclopropanations. Heteroaryldiazoacetates containing both electron-rich and electron-deficient heterocycles, such as thiophene, furan, pyridine, indole, oxazole, isoxazole, and benzoxazole, are effective in this chemistry. These studies broaden the range of diazo compounds containing both electron-withdrawing and electron-donating groups, which undergo highly diastereoselective cyclopropanations.