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6597746 
Journal Article 
A practical synthesis of (R)-(-)-phenylephrine hydrochloride 
Gurjar, MK; Krishna, LM; Sarma, B; Chorghade, MS; , 
1998 
1 
Organic Process Research and Development
ISSN: 1083-6160 
AMER CHEMICAL SOC 
WASHINGTON 
2 
6 
422-424 
English 
WOS:000077191600015 
(R)-(-)-Phenylephrine hydrochloride is a clinically potent adrenergic agent and beta-receptor sympathomimetic drug, exclusively marketed in the optically active form, An asymmetric synthesis has been developed with high enantiomeric excess based on hydrolytic kinetic resolution of a styrene oxide derivative using (R,R)-SalenCo(III)OAc complex.