Microsomal and cytosolic epoxide hydrolase in Drosophila melanogaster | Health & Environmental Research Online (HERO)

Health & Environmental Research Online (HERO)

Print Feedback Export to File

This record has one attached file:

Citation
Tags

HERO ID

6599023

Reference Type

Journal Article

Title

Microsomal and cytosolic epoxide hydrolase in Drosophila melanogaster

Author(s)

Jansen, M; Baars, AJ; Breimer, DD; ,

Year

1986

Is Peer Reviewed?

Yes

Journal

Biochemical Pharmacology
ISSN: 0006-2952
EISSN: 1873-2968

Publisher

PERGAMON-ELSEVIER SCIENCE LTD

Location

OXFORD

Volume

Issue

Page Numbers

2229-2232

Language

English

PMID

3089226

DOI

10.1016/0006-2952(86)90596-4

Web of Science Id

WOS:A1986D010400027

URL

https://www.scopus.com/inward/record.uri?eid=2-s2.0-0022478673&doi=10.1016%2f0006-2952%2886%2990596-4&partnerID=40&md5=84e42cef614211e67e4430f360febd52
Exit

Abstract

Subcellular fractions from Drosophila melanogaster and rat liver were investigated on their epoxide hydrolase activity. Both microsomes and the post-microsomal supernatant of Drosophila appeared to contain epoxide hydrolase activity using styrene-7,8-oxide as the substrate. Based on body weight, these activities were in the same order of magnitude. Rat liver cytosol was able to catalyze the hydrolysis of styrene oxide only if the glutathione S-transferase activity was blocked.