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6601247 
Journal Article 
EFFICIENT IMMOBILIZATION OF PROTEIN ON MONODISPERSED COLLOIDAL SILICA PARTICLES MODIFIED BY COPOLYMERS OF MALEIC-ANHYDRIDE AND STYRENE OR METHYL-METHACRYLATE 
Yoshinaga, K; Kondo, K; Kondo, A; , 
1995 
1 
Polymer Journal
ISSN: 0032-3896 
SOC POLYMER SCIENCE JAPAN 
TOKYO 
27 
1 
98-100 
English 
WOS:A1995QJ19200012 
An improved method for the immobilization of bovine serum albumin (BSA) on monodispersed colloidal silica particles is described. The particles were modified with the copolymer of maleic anhydride and styrene or methyl methacrylate. The applicability of the hybrid particles to the immunological agglutination test is examined. 
Biomaterial carrier; Hybrid particles; Immunological agglutination test; Maleic anhydride copolymer; Monodispersed colloidal silica; Protein immobilization; Surface modification