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Citation
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HERO ID
6606902
Reference Type
Legal Material
Subtype
Patent
Title
Ropinirole-containing adhesive patch
Author(s)
Inoo, K; Katayama, A; Takano, D
Year
2018
Publisher
Teikoku Seiyaku Co Ltd
Web of Science Id
BCI:BCI201800702889
Abstract
A patch containing free ropinirole (ropinirole in free form) in an adhesive base is provided, in which the patch exhibits favorable and continuous transdermal absorbability, high drug stability, and excellent adhesiveness. A transdermal absorption patch includes free ropinirole added to an adhesive base that contains a styrene-isoprene-styrene block copolymer (SIS), one or two or more tackifier resins containing a rosin-based resin, and a softener. The transdermal absorption patch is characterized in that the compounding ratio of the rosin-based resin to the free ropinirole represented as the ratio of the weight of the combined rosin-based resin to the free ropinirole is 3.5 to 8.0. In particular, a ropinirole-containing patch wherein the rosin-based resin is a hydrogenated rosin glycerol ester and the softener is liquid paraffin is provided.
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