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6617264 
Journal Article 
Synthesis of alpha-hydroxy esters by glyoxylate-ene reaction in Lewis acid chloroaluminate ionic liquids 
Shen, ZL; He, XJ; Mo, WM; Xie, Y; Hu, BX; Sun, N; , 
2006 
1 
Chinese Journal of Catalysis
ISSN: 1872-2067 
SCIENCE PRESS 
BEIJING 
197-199 
WOS:000236753400002 
The chloroaluminate ionic liquid, composed of AlCl3 and 1-butyl-3-methylimidazolium chloride ([bmim]Cl), is used as the solvent and catalyst to synthesize a-hydroxy esters from alkene and glyoxylate via the glyoxylate-ene reaction. Under the reaction conditions of 15 degrees C, 4 h, and AlCl3/[bmim] Cl molar ratio of 2, the ethyl alpha-hydroxy-4-phenyl-4-pentenoate with high yield (95.2%) is obtained in the reaction of alpha-methyl styrene and ethyl glyoxylate. Other alpha-hydroxy esters can also be obtained in high yields through the glyoxylateene reaction. Moreover, the chloroaluminate ionic liquid can be reused several times.