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HERO ID
664761
Reference Type
Journal Article
Title
Sister chromatid exchange (SCE) and micronucleus (MN) frequencies in lymphocytes of gasoline station attendants
Author(s)
Bukvic, N; Bavaro, P; Elia, G; Cassano, F; Fanelli, M; Guanti, G
Year
1998
Is Peer Reviewed?
Yes
Journal
Mutation Research
ISSN:
0027-5107
EISSN:
1873-135X
Volume
415
Issue
1-2
Page Numbers
25-33
Language
English
PMID
9711259
DOI
10.1016/S1383-5718(98)00045-X
Web of Science Id
WOS:000075065900003
Abstract
Peripheral blood lymphocytes from 22 men with low average exposure (229 micrograms/m3 = 0.72 ppm) to benzene and 19 control men were investigated for Sister Chromatid Exchange (SCE) frequency. The majority of the men (21 exposed, 19 controls) were also investigated using the micronucleus assay (MN). The exposed subjects were employed at 10 different gas stations in or near the city (Bari/South Italy). SCE frequencies were significantly related with age and smoking habits, on the contrary no relation was observed between SCE and length of employment (SCE = 7.41 + 0.03.age (*) + 0.0001.length of employment (n.s.) + 0.03.cigarette consumption (*); F = 4.87; p < 0.01; (*) significant; (n.s.) non-significant). MN frequencies were significantly increased in relation with length of employment; but no relation was observed when age and smoking habits were taken into consideration (regression model: MN = 18.03 + 0.006.age (n.s.) + 0.32.length of employment (*) - 0.1.cigarette consumption (n.s.); F = 4.138; p < 0.05).
Keywords
sister chromatid exchange; micronucleus; benzene; gasoline station attendant; human biomonitoring
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