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HERO ID
6648461
Reference Type
Journal Article
Title
Fluoride Absorption through the Hamster Cheek Pouch: A pH=dependent Event
Author(s)
Whitford, GM; Callan, RS; Wang, HS; ,
Year
1982
Is Peer Reviewed?
Yes
Journal
Journal of Applied Toxicology
ISSN:
0260-437X
EISSN:
1099-1263
Publisher
WILEY
Location
HOBOKEN
Page Numbers
303-306
PMID
7185910
Web of Science Id
WOS:000481581200007
Abstract
The fractional absorptions of fluoride, 3H20, lZ51 and 14C-DM0 from the hamster cheek pouch were determined as functions of solution pH. When the pH was < 5, fluoride absorption rate was inversely related to pH. The absorption rates of the other substances were not influenced by pH. The fractional absorptions of fluoride and 3Hz0 were independent of fluoride concentrations over the range 1-53 mM. The data indicate that the absorption of fluoride through this keratinized epithelium occurs mainly by the diffusion of non-ionic HF.
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