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6653699 
Journal Article 
Adsorption of bovine serum albumin onto polystyrene latex particles bearing saccharidic moieties 
Revilla, J; Elaissari, A; Carriere, P; Pichot, C; , 
1996 
Yes 
Journal of Colloid and Interface Science
ISSN: 0021-9797
EISSN: 1095-7103 
ACADEMIC PRESS INC JNL-COMP SUBSCRIPTIONS 
SAN DIEGO 
180 
2 
405-412 
English 
WOS:A1996UT35000012 
The adsorption of bovine serum albumin (BSA) onto polystyrene latexes bearing various amounts of sugar moieties has been investigated as a function of pH and ionic strength and the results were compared to those for bare polystyrene latexes having negative surface charges. The functionalized latexes were produced by seeded copolymerization of (0.3 mu m) liposaccharidic monomer onto polystyrene particles obtained by soap-free emulsion polymerization of styrene using potassium persulfate as initiator. At first, the electrophoretic mobility behavior of the various latexes was examined as a function of pH: a significant decrease was observed in the case of saccharide-containing latex particles compared to the bare particles. The adsorption of BSA onto these latexes exhibited a reduced amount of adsorbed BSA for those latex particles bearing saccharide groups. This adsorbed amount depends on the yield of saccharidic monomer incorporated onto the surfaces of the latex particles. (C) 1996 Academic Press, Inc. 
adsorption; bovine serum albumin; polystyrene latex; saccharidic moieties