Health & Environmental Research Online (HERO)


Print Feedback Export to File
6660509 
Journal Article 
The structure of C-polysaccharide from the walls of Streptococcus pneumoniae 
Poxton, IR; Tarelli, E; Baddiley, J; , 
1978 
Yes 
Biochemical Journal
ISSN: 0264-6021
EISSN: 1470-8728 
PORTLAND PRESS LTD 
LONDON 
1033-1042 
English 
33662 
WOS:A1978GA06500033 
The well-known immologically active component of pneumococci, C-polysaccharide, is a teichoic acid that can be isolated from the cell walls and purified by Sephadex and ion-exchange chromatography. Further details of the structure of C-teichoic acid were established by chemical degradation, including hydrolysis in acid and alkali, treatment with HF, periodate oxidation and methylation. In addition, the use of 13C n.m.r. has confirmed some of these structural features and resulted in a proposal for the order of substituents, the location of positions of substitution and the configuration of anomeric centres in the repeating unit of the polymer.