Adverse reaction and rational use of paracetamol tablets and its drug content detection based on spectral test | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

6685007

Reference Type

Journal Article

Title

Adverse reaction and rational use of paracetamol tablets and its drug content detection based on spectral test

Author(s)

Shanting, M; Qing, X

Year

2018

Is Peer Reviewed?

Journal

Pakistan Journal of Pharmaceutical Sciences
ISSN: 1011-601X

Publisher

UNIV KARACHI

Location

KARACHI

Volume

Issue

4(Special)

Page Numbers

1743-1749

Language

English

PMID

30203773

Web of Science Id

WOS:000444221300028

Abstract

Paracetamol and amantadine hydrochloride tablet is a commonly used drug to relieve the common cold. Its main ingredient is 4-Acetamidophenol. The safety of acetaminophen containing cold drugs has attracted more and more attention in recent years. In order to promote the clinical safety of drugs, the adverse reaction and clinical application of acetaminophen drugs are analyzed in this paper. The adverse reactions induced by acetaminophen mainly include: allergic reaction (46.1%), liver and kidney injury (25%), blood system (15.7%) and digestive system (5.2%). At the same time, we tested the content of acetaminophen by using spectral test. It can be seen that the method can be extended to the quantitative analysis and quality control of the effective components of other compound drugs.