US EPA

6726766 

Journal Article 

Atmospheric particulate matters in an Indian urban area: Health implications from potentially hazardous elements, cytotoxicity, and genotoxicity studies 

Islam, N; Dihingia, A; Khare, P; Saikia, BK; , 

2020 

Yes 

Journal of Hazardous Materials
ISSN: 0304-3894
EISSN: 1873-3336 

ELSEVIER 

AMSTERDAM 

31733994 

10.1016/j.jhazmat.2019.121472 

WOS:000508742700093 

The nature of the atmospheric particulate matters (PMs) varies depending on their sizes and their origin from different activities in the background environment. These PMs are associated with potentially hazardous elements (PHEs) such as organic compounds (e.g. Polyaromatic Hydrocarbons) that can be harmful to health. The main objective of this work is the identification and investigation of the toxicological aspects of PHEs in PMs during pre-monsoon and post-monsoon season in an urban area of Northeast region (NER) of India. In the course of the study, the 24 -hs average concentrations of PMs were detected to be more than two-times higher than the Indian standard limit (NAAQ, category) which indicates poor air quality in both the seasons around the sampling sites. This study demonstrates that the concentrations of PM-bound PAHs are mutagenic and that the Excess Cancer Risks exceed the USEPA standard limits. PMs cause cytotoxicity and can also induce genotoxicity to human health analyzed by cell culture and gel electrophoresis. This study helps to promote research to evaluate the PMs bound PHEs toxicity in diverse human cell lines and also their relationship with climatic factors as well as quantitative source apportionment for mitigation purposes.