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6771910 
Journal Article 
[Risk factors of development of left ventricular hypertrophy in patients with hypertensive disease with high compliance to treatment] 
Koziolova, NA; Shatunova, IM; Lazarev, IA 
2012 
1 
Kardiologiya
ISSN: 0022-9040 
52 
4 
25-30 
Russian 
22839513 
WOS:000304230600004 
Aim of the study was to assess rate of development of left ventricular hypertrophy (LVH) and its risk factors in patients with hypertensive disease (HD) without target organs damage with high compliance to treatment. We included in this prospective cohort study 428 patients with HD without target organs damage. Duration of follow-up was 8.8+/-2.6 years. Rate of LVH development was 36.9%. It was more frequent in men (41.3%) than in women (32.7%). Intensity of antihypertensive therapy was higher in a group of patients with with left ventricular remodeling. Risk of development of LVH was associated with age especially in men older than 55 years, duration of hypertension, body mass, initial level of diastolic blood pressure, pulse blood pressure, level of low density lipoprotein cholesterol, and fasting level of glucose in blood plasma. Thus in patients with HD rate of LVH development at the background of high compliance to treatment is lower than in total population and has definite specific patterns.